Lymphocyte chromosome breakage in low benzene exposure among Indonesian workers
نویسندگان
چکیده
Latar belakang: Benzena sudah digunakan sejak lama dalam industri dan penggunaannya cenderung meningkat sehingga memerlukan pengendalian. Walaupun benzena industri dikendalikan < 1 ppm, namun efeknya masih terlihat, antara lain berupa patahan kromosom limfosit. Penelitian ini bertujuan mengevaluasi patahan kromosom limfosit sebagai efek pajanan benzena kurang 1 ppm di lingkungan kerja, dan faktor risiko yang berhubungan.
منابع مشابه
Characterization and mechanisms of chromosomal alterations induced by benzene in mice and humans.
Elevated frequencies of chromosomal aberrations have been observed in the lymphocytes of benzene-exposed workers. Similar changes occurring in the bone marrow may play an important role in the development of leukemia. The objective of this research has been to characterize chromosomal alterations induced by benzene in mice and humans and to investigate the potential role of inhibition of topois...
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